Most rapid weight loss medicines for obesity work by making you feel less hungry or making you feel full sooner. They are used together with very low calorie diet and exercise. Medicine is generally used only for those who have a body mass index (BMI) of 30 or higher. But they sometimes are used for those with a BMI of 27 or higher who are at risk for high blood pressure,lipid metabolism, coronary artery disease, type 2 Diebetes and sleep apnea. Orlistat (Alli) is also available over the counter. Alli contains half of the medicine that is in Xenical. Over-the-counter orlistat is not meant for use by anyone under the age of 18.

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